Senior Scientist I, Analytical Development
Company Description
About AbbVie AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us atwww.abbvie.com. Follow @abbvie onLinkedIn,Facebook,Instagram,XandYouTube.
Job Description
The Opportunity
We seek a Senior Scientist I, Analytical Development to join an experienced, fast-paced and collaborative team. This position will be primarily responsible for supporting characterization of AbbVies mRNA-based targeted lipid nanoparticles (tLNPs) pipeline. This role will focus on executing testing methods for characterizing mRNA/tLNPs and supporting development of new tLNP characterization methods. Working collaboratively across the discovery research team, this position will support process/product characterization, expansion of the mRNA/tLNP pipeline, method development, and platform development. Responsibilities & Duties: - Independently perform icIEF, HPLC, CE, and plate-based assay testing of mRNA and tLNP products for characterizing content, purity/impurities, and integrity
- Support development of novel nanoparticle characterization techniques, including but not limited to icIEF, SEC, MALS, CZE, LC-MS, etc
- Re-optimize analytical methods to support new programs and platform improvements
- Improve routine assay efficiency through automation and assay/workflow improvements
- Author technical reports and documents as needed
Qualifications
- Bachelors, Masters, or Ph.D. in Analytical Chemistry typically with a minimum of 10 (BS), 8 (MS), or 0 (Ph.D.) years related industry experience.
- Strong technical background in analytical chemistry, excellent analytical problem-solving skills. Capable of independently developing and troubleshooting analytical methods.
- Degree in Biochemistry, Chemistry, Bioengineering, Chemical Engineering or related field with experience testing and developing analytical characterization methods for biologics (e.g. antibodies, mRNA, etc) is required.
- Experience with nanoparticle and/or small molecule characterization is preferred
- Demonstrate creative 'out of the box' thinking to solve difficult problems
- Experience with icIEF, HPLC, Capillary Electrophoresis (CE), and plate-based assays required
- Proficiency authoring and reviewing technical reports
- Strong communication skills, both written and verbal, with a demonstrated capacity to thrive in collaborative, team-driven environments.
Additional Information
Applicable only to applicants applying to a position in any location with pay disclosure requirements under state orlocal law: The compensation range described below is the range of possible base pay compensation that the Companybelieves ingood faith it will pay for this roleat thetimeofthis posting based on the job grade for this position.Individualcompensation paid within this range will depend on manyfactors including geographiclocation,andwemay ultimately pay more or less than the posted range. This range may bemodified in thefuture. We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick),medical/dental/visioninsurance and 401(k) to eligibleemployees. This job is eligible toparticipate in our short-term incentiveprograms.
Note: No amount of payis considered to bewages or compensation until such amount isearned, vested, anddeterminable.Theamountandavailabilityof anybonus,commission, incentive, benefits, or any other form ofcompensation and benefitsthat areallocable to a particular employeeremains in the Company'ssoleandabsolutediscretion unless and until paid andmay bemodified at the Companys sole and absolutediscretion, consistent withapplicable law. AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled. US & Puerto Rico only - to learn more, visithttps://www.abbvie.com/join-us/equal-employment-opportunity-employer.html US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more: https://www.abbvie.com/join-us/reasonable-accommodations.html
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