About AbbVie

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us atwww.abbvie.com. Follow @abbvie onLinkedIn,Facebook,Instagram,XandYouTube.

Purpose

This position brings anopportunity to make innovative contributions that will define how AbbVie leverages AI-enabled drug discovery across our small molecule portfolio.Reports to Head of Computational Drug Discovery (CDD) and will lead thecomputationalHitGen/LeadGen(HGLG)team.Will implement and enableclosecollaborationbetweenmembersof theHGLGteamandpartners in the Target Enabling Technologies (TET) andGlobal Medicinal Chemistry(GMEC)teams. Mustpossessa strongexpertisein modernmedicinal chemistry, including a deep understanding of modern computational and experimentalstrategies,andproperty-based drug design. The ideal candidate will have a strong and established backgroundfrom having worked ona broad range of diverseearly-stagecampaigns,andan established external footprint and network.Past experiencewillhave includedmentorship of early/mid-career scientists in matrixed and/or direct reporting relationships.

Responsibilities

• Consultwithprojectteam toestablishdesirableproject-relevant hit/leadcriteria,andassigning anHGLGmember totheproject teamthat can execute these goalsforaccelerated identification ofsuitable chemical matter

• GuideHGLGmembers inbenchmarkingexperiments to evaluatemodels performance and domain of applicability

• Clearly communicatetoproject teamstherationaleforselectingspecific approachesand how theysuitproject needs

• Leaddevelopment of a cohesivecollection ofcutting-edgemethodsand workflows, tocomprehensivelyaddress AbbVies small moleculeportfolioneeds (methods forpredictingbinding affinities of diverse chemotypes,forpredict pharmacological propertiesfor diverse chemotypes(PK parameters, etc.), andforrapidlysamplingbothenumeratedandAI-generatedchemical spaces

• Workclosely with theTET andGMEC leadership teamstoidentifyand addressgapswhere computational predictions are needed

• Advance scientificexpertisewithin theHGLGteamand collaborate with cross-disciplinaryteams from CDD and InformationResearchto advance programs and ensure computational capabilities are bestimplemented across programs

• Proactivelydemonstrateleadership by providing expert advice and shared knowledge with directreports, peers, and senior management

• Identifyand integrate emerging scientific trends from internal and external sources into functionalobjectives

• Present program updates and research strategies to functional and non-functional leaders as wellas potential and existing partners

• Maintain awareness of emerging literature and science in the field and author scientificdisclosures/publications

• Maintain scientific presence outside AbbVie withappropriate publicationand conference abstractsubmission highlighting innovativelearnings in computationalmedicinal chemistry

Qualifications

• Bachelors Degree or equivalent education inscience-related field with extensive (typically > 18years) of related work;Masters Degreeor equivalent education with extensive (typically > 16 years) of related work; PhD in Science or related field with typically 10+ years of related workexperience

• Highly organized and self-directed, experience leading multiple complex simultaneous research programs or initiatives

• Extensive knowledge and experience inapplying data science approachesfordrug discovery

• Extensive knowledge and experience in moderncomputational approaches fordrug discovery

• Excellent written and verbal communication,as well as critical evaluation and data-driven decision making, particularlyincluding an ability to explain complex ideas to non-specialists

• Strong analytical and problem-solving skills withdemonstratedability to think critically and creatively, and provide solutions both individually and collaboratively with internal experts

• Proven team leadership and management abilities, including experience mentoring, guiding, supervising, and developing scientific personnel with various backgrounds and training levels

• Highly collaborative, team-oriented, and considerate of the needs of others

• Strong interpersonal skills and ability to collaborate with diverse groups within the organization and external partners

• Ability to create an inclusive environment where diverse ideas, viewpoints and backgrounds are valued; willingness and ability to lead inclusively anddemonstratea commitment to listen and consider all points of view

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state orlocal law:

• The compensation range described below is the range of possible base pay compensation that the Companybelieves ingood faith it will pay for this role at the timeof thisposting based on the job grade for this position.Individualcompensation paid within this range will depend on many factors including geographic location,andwemayultimatelypaymore or less than the posted range. This range may bemodifiedin thefuture.

• We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick),medical/dental/visioninsurance and 401(k) to eligibleemployees.

• This job is eligible toparticipatein our long-term incentiveprograms.

Note: No amount of payis considered to bewages or compensation until such amount is earned, vested, anddeterminable.The amount and availability of any bonus,commission,incentive, benefits, or any other form ofcompensation and benefitsthat are allocable to a particular employeeremainsin the Company's sole andabsolutediscretion unless anduntil paid andmay bemodifiedat the Companys sole and absolute discretion, consistent withapplicable law.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.

US & Puerto Rico only - to learn more, visithttps://www.abbvie.com/join-us/equal-employment-opportunity-employer.html

US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:

https://www.abbvie.com/join-us/reasonable-accommodations.html